T Cell Responses to Neural Autoantigens Are Similar in Alzheimer’s Disease Patients and Age-Matched Healthy Controls

T Cell Responses to Neural Autoantigens Are Similar in Alzheimer’s Disease Patients and Age-Matched Healthy Controls

Alzheimer’s disease (AD), a chronic multifactorial and complex neurodegenerative disorder is a leading cause of dementia. Recently, neuroinflammation has been hypothesized as a contributing factor to AD pathogenesis. The role of adaptive immune responses against neuronal antigens, which can either c...

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Bibliographic Details
Main Authors: Rekha Dhanwani, John Pham, Ashmitaa Logandha Ramamoorthy Premlal, April Frazier, Atul Kumar, Maria Elena Pero, Francesca Bartolini, Juliana Rezende Dutra, Karen S. Marder, Bjoern Peters, David Sulzer, Alessandro Sette, Cecilia S. Lindestam Arlehamn
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer’s disease
neurodegenration
autoimmunity
T cell responses
transcriptomics
neuroantigens
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00874/full

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https://www.frontiersin.org/article/10.3389/fnins.2020.00874/full

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