Network analyses reveal pervasive functional regulation between proteases in the human protease web.

Network analyses reveal pervasive functional regulation between proteases in the human protease web.

Proteolytic processing is an irreversible posttranslational modification affecting a large portion of the proteome. Protease-cleaved mediators frequently exhibit altered activity, and biological pathways are often regulated by proteolytic processing. Many of these mechanisms have not been appreciate...

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Bibliographic Details
Main Authors: Nikolaus Fortelny, Jennifer H Cox, Reinhild Kappelhoff, Amanda E Starr, Philipp F Lange, Paul Pavlidis, Christopher M Overall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24865846/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24865846/?tool=EBI

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