Meta-Analysis of Large-Scale Toxicogenomic Data Finds Neuronal Regeneration Related Protein and Cathepsin D to Be Novel Biomarkers of Drug-Induced Toxicity.

Undesirable toxicity is one of the main reasons for withdrawing drugs from the market or eliminating them as candidates in clinical trials. Although numerous studies have attempted to identify biomarkers capable of predicting pharmacotoxicity, few have attempted to discover robust biomarkers that ar...

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Bibliographic Details
Main Authors: Hyosil Kim, Ju-Hwa Kim, So Youn Kim, Deokyeon Jo, Ho Jun Park, Jihyun Kim, Sungwon Jung, Hyun Seok Kim, KiYoung Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4559398?pdf=render