Homopolish: a method for the removal of systematic errors in nanopore sequencing by homologous polishing
Abstract Nanopore sequencing has been widely used for the reconstruction of microbial genomes. Owing to higher error rates, errors on the genome are corrected via neural networks trained by Nanopore reads. However, the systematic errors usually remain uncorrected. This paper designs a model that is...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-021-02282-6 |