Gastroprotective effects and metabolomic profiling of Chasteberry fruits against indomethacin-induced gastric injury in rats

Gastroprotective effects and metabolomic profiling of Chasteberry fruits against indomethacin-induced gastric injury in rats

Vitex agnus castus L. extract (VACE) was investigated for its gastroprotective properties and possible molecular mechanisms in rats. VACE (60 or 120 mg/kg) or Esomeprazole (20 mg/kg) were orally administered for 3 weeks before the induction of gastropathy using indomethacin (30 mg/kg, single oral do...

Full description

Bibliographic Details
Main Authors: Hanan A. Ogaly, Muhammad A. Alsherbiny, Shymaa A. El Badawy, Reham M. Abd-Elsalam, Chun Guang Li, Asmaa A. Azouz
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Journal of Functional Foods
Subjects:
Indomethacin
Gastric injury
Vitex agnus castus
Apoptosis
NF-κB signalling
Metabolomic profiling
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621003819

Internet

http://www.sciencedirect.com/science/article/pii/S1756464621003819

Similar Items