Integrating in silico and in vitro analysis of peptide binding affinity to HLA-Cw*0102: a bioinformatic approach to the prediction of new epitopes.

Integrating in silico and in vitro analysis of peptide binding affinity to HLA-Cw*0102: a bioinformatic approach to the prediction of new epitopes.

Predictive models of peptide-Major Histocompatibility Complex (MHC) binding affinity are important components of modern computational immunovaccinology. Here, we describe the development and deployment of a reliable peptide-binding prediction method for a previously poorly-characterized human MHC cl...

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Bibliographic Details
Main Authors: Valerie A Walshe, Channa K Hattotuwagama, Irini A Doytchinova, Mailee Wong, Isabel K Macdonald, Arend Mulder, Frans H J Claas, Pierre Pellegrino, Jo Turner, Ian Williams, Emma L Turnbull, Persephone Borrow, Darren R Flower
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2779488?pdf=render

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http://europepmc.org/articles/PMC2779488?pdf=render

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