Dimeric RNA recognition regulates HIV-1 genome packaging.

How retroviruses regulate the amount of RNA genome packaged into each virion has remained a long-standing question. Our previous study showed that most HIV-1 particles contain two copies of viral RNA, indicating that the number of genomes packaged is tightly regulated. In this report, we examine the...

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Bibliographic Details
Main Authors: Olga A Nikolaitchik, Kari A Dilley, William Fu, Robert J Gorelick, S-H Sheldon Tai, Ferri Soheilian, Roger G Ptak, Kunio Nagashima, Vinay K Pathak, Wei-Shau Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3605237?pdf=render