Understanding the Roles of the Kynurenine Pathway in Multiple Sclerosis Progression

The kynurenine pathway (KP) is a major degradative pathway of tryptophan ultimately leading to the production of nicotinamide adenine dinucleotide (NAD+) and is also one of the major regulatory mechanisms of the immune response. The KP is known to be involved in several neuroinflammatory disorders i...

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Bibliographic Details
Main Authors: Chai K. Lim, Bruce J. Brew, Gayathri Sundaram, Gilles J. Guillemin
Format: Article
Language:English
Published: SAGE Publishing 2010-08-01
Series:International Journal of Tryptophan Research
Online Access:http://la-press.com/understanding-the-roles-of-the-kynurenine-pathway-in-multiple-sclerosi-a2237