Modulation of androgen receptor signaling in hormonal therapy-resistant prostate cancer cell lines.

<h4>Background</h4>Prostate epithelial cells depend on androgens for survival and function. In (early) prostate cancer (PCa) androgens also regulate tumor growth, which is exploited by hormonal therapies in metastatic disease. The aim of the present study was to characterize the androgen...

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Bibliographic Details
Main Authors: Rute B Marques, Natasja F Dits, Sigrun Erkens-Schulze, Wilfred F J van Ijcken, Wytske M van Weerden, Guido Jenster
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21829708/?tool=EBI