ATF2-Induced lncRNA GAS8-AS1 Promotes Autophagy of Thyroid Cancer Cells by Targeting the miR-187-3p/ATG5 and miR-1343-3p/ATG7 Axes

ATF2-Induced lncRNA GAS8-AS1 Promotes Autophagy of Thyroid Cancer Cells by Targeting the miR-187-3p/ATG5 and miR-1343-3p/ATG7 Axes

Long non-coding RNAs (lncRNAs) play an essential regulatory role in multiple cancers. However, the role of lncRNAs in papillary thyroid carcinoma (PTC) is still unknown. Here, GAS8-AS1, a novel lncRNA that is significantly downregulated in PTC, was selected for further investigation. The roles of GA...

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Bibliographic Details
Main Authors: Yuan Qin, Wei Sun, Zhihong Wang, Wenwu Dong, Liang He, Ting Zhang, Liang Shao, Hao Zhang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
GAS8-AS1
lncRNA
thyroid cancer
autophagy
transcription factor
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120302936

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http://www.sciencedirect.com/science/article/pii/S2162253120302936

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