Large-scale microcarrier culture of HEK293T cells and Vero cells in single-use bioreactors

Large-scale microcarrier culture of HEK293T cells and Vero cells in single-use bioreactors

Abstract Gene therapy and viral vaccine are becoming attractive therapeutic options for the treatment of different malignant diseases. Viral vector productions are often using static culture vessels and small volume stainless steel bioreactors (SSB). However, the yield of each vessel can be relative...

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Bibliographic Details
Main Authors: Jianjun Yang, Patrick Guertin, Guodong Jia, Zhongliang Lv, Hongyan Yang, Dianwen Ju
Format: Article
Language:English
Published: SpringerOpen 2019-05-01
Series:AMB Express
Subjects:
Process scale-up
HEK293T cells
Vero cells
Microcarriers
Bead-to-bead transfer
Single-use Bioreactor
Online Access:http://link.springer.com/article/10.1186/s13568-019-0794-5

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http://link.springer.com/article/10.1186/s13568-019-0794-5

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