Targeted Modification of the Foot-And-Mouth Disease Virus Genome for Quick Cell Culture Adaptation

Foot-and-mouth disease virus (FMDV) causes the highly contagious foot-and-mouth disease, which is characterized by the appearance of vesicles in and around the mouth and feet of cloven-hoofed animals. BHK-21 cells are the cell line of choice for the propagation of FMDV for vaccine production worldwi...

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Bibliographic Details
Main Authors: Veronika Dill, Aline Zimmer, Martin Beer, Michael Eschbaumer
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/4/583