Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway

Pathogenic microbes can often attach to surfaces and form biofilms that display increased antibiotic resistance. Here, the authors characterize the biosynthesis of a new class of natural products, the cahuitamycins, that inhibit formation of biofilms by the pathogenic bacterium Acinetobacter baumann...

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Bibliographic Details
Main Authors: Sung Ryeol Park, Ashootosh Tripathi, Jianfeng Wu, Pamela J. Schultz, Isaiah Yim, Thomas J. McQuade, Fengan Yu, Carl-Johan Arevang, Abraham Y. Mensah, Giselle Tamayo-Castillo, Chuanwu Xi, David H. Sherman
Format: Article
Language:English
Published: Nature Publishing Group 2016-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10710