Whole-genome amplification in double-digest RADseq results in adequate libraries but fewer sequenced loci

Whole-genome amplification by multiple displacement amplification (MDA) is a promising technique to enable the use of samples with only limited amount of DNA for the construction of RAD-seq libraries. Previous work has shown that, when the amount of DNA used in the MDA reaction is large, double-dige...

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Bibliographic Details
Main Authors: Bruno A. S. de Medeiros, Brian D. Farrell
Format: Article
Language:English
Published: PeerJ Inc. 2018-07-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/5089.pdf