Impact of a Rapid Decline in Malaria Transmission on Antimalarial IgG Subclasses and Avidity

Impact of a Rapid Decline in Malaria Transmission on Antimalarial IgG Subclasses and Avidity

Understanding how immunity to malaria is affected by declining transmission is important to aid vaccine design and understand disease resurgence. Both IgG subclasses and avidity of antigen-specific responses are important components of an effective immune response. Using a multiplex bead array assay...

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Bibliographic Details
Main Authors: Isaac Ssewanyana, John Rek, Isabel Rodriguez, Lindsey Wu, Emmanuel Arinaitwe, Joaniter I. Nankabirwa, James G. Beeson, Harriet Mayanja-Kizza, Philip J. Rosenthal, Grant Dorsey, Moses R. Kamya, Chris Drakeley, Bryan Greenhouse, Kevin K. A. Tetteh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
antibody avidity
Plasmodium falciparum
immunity
IgG subclass antibodies
avidity index
malaria
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.576663/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.576663/full

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