Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults

Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults

Administration of ethanol to rodents during the synaptogenesis period induces extensive apoptotic neurodegeneration in the developing brain. This neurotoxicity may explain the reduced brain mass and neurobehavioral disturbances in human Fetal Alcohol Syndrome (FAS). Here, we report binge-like exposu...

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Bibliographic Details
Main Authors: David F. Wozniak, Richard E. Hartman, Maureen P. Boyle, Sherri K. Vogt, Ashley R. Brooks, Tatyana Tenkova, Chainllie Young, John W. Olney, Louis J. Muglia
Format: Article
Language:English
Published: Elsevier 2004-12-01
Series:Neurobiology of Disease
Subjects:
Apoptosis
Behavior
Fetal Alcohol Syndrome
Hippocampus
Mice
Thalamus
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104001913

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http://www.sciencedirect.com/science/article/pii/S0969996104001913

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