Synthesis of 6-Membered-Ring Fused Thiazine-Dicarboxylates and Thiazole-Pyrimidines via One-Pot Three-Component Reactions

Synthesis of 6-Membered-Ring Fused Thiazine-Dicarboxylates and Thiazole-Pyrimidines via One-Pot Three-Component Reactions

A facile and efficient one-pot three-component reaction method for the synthesis of thiazine-dicarboxylates is reported. Reaction of an isocyanide and dialkyl acetylenedicarboxylate with 2-amino-4<i>H</i>-1,3-thiazin-4-one derivatives containing both an acidic proton and an internal nucl...

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Bibliographic Details
Main Authors: Reagan L. Mohlala, Elena Mabel Coyanis, Muhammad Q. Fish, Manuel A. Fernandes, Moira L. Bode
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
multicomponent reaction
isocyanides
dialkyl acetylenedicarboxylates
thiourea
α-haloketone
thiazine
Online Access:https://www.mdpi.com/1420-3049/26/18/5493

Internet

https://www.mdpi.com/1420-3049/26/18/5493

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