A Novel Fibroblast Reporter Cell Line for in vitro Studies of Pulmonary Fibrosis

A Novel Fibroblast Reporter Cell Line for in vitro Studies of Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal disease of the lower respiratory tract with restricted therapeutic options. Repetitive injury of the bronchoalveolar epithelium leads to activation of pulmonary fibroblasts, differentiation into myofibroblasts and excessive extracellular matrix (ECM) de...

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Bibliographic Details
Main Authors: Julia Nemeth, Annika Schundner, Karsten Quast, Veronika E. Winkelmann, Manfred Frick
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Physiology
Subjects:
idiopathic pulmonary fibrosis
lung
myofibroblast
TGF-β
extracellular matrix
alpha smooth muscle actin
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.567675/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.567675/full

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