Generation of a novel regulatory NK cell subset from peripheral blood CD34+ progenitors promoted by membrane-bound IL-15.

Generation of a novel regulatory NK cell subset from peripheral blood CD34+ progenitors promoted by membrane-bound IL-15.

BACKGROUND: NK cells have been long time considered as cytotoxic lymphocytes competent in killing virus-infected cells and tumors. However, NK cells may also play essential immuno-regulatory functions. In this context, the real existence of a defined NK subset with negative regulatory properties has...

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Bibliographic Details
Main Authors: Massimo Giuliani, Julien Giron-Michel, Simone Negrini, Paola Vacca, Deniz Durali, Anne Caignard, Caroline Le Bousse-Kerdiles, Salem Chouaib, Aurore Devocelle, Rajia Bahri, Antoine Durrbach, Yassine Taoufik, Silvano Ferrini, Michela Croce, Maria Cristina Mingari, Lorenzo Moretta, Bruno Azzarone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2376096?pdf=render

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http://europepmc.org/articles/PMC2376096?pdf=render

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