Intratumoral administration of astatine-211-labeled gold nanoparticle for alpha therapy

Intratumoral administration of astatine-211-labeled gold nanoparticle for alpha therapy

Abstract Background 211At is a high-energy α-ray emitter with a relatively short half-life and a high cytotoxicity for cancer cells. Its dispersion can be imaged using clinical scanners, and it can be produced in cyclotrons without the use of nuclear fuel material. This study investigated the biodis...

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Bibliographic Details
Main Authors: Hiroki Kato, Xuhao Huang, Yuichiro Kadonaga, Daisuke Katayama, Kazuhiro Ooe, Atsushi Shimoyama, Kazuya Kabayama, Atsushi Toyoshima, Atsushi Shinohara, Jun Hatazawa, Koichi Fukase
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Journal of Nanobiotechnology
Subjects:
Astatine-211
Alpha emitters
Gold nanoparticles
Radiolabeling
Cancer therapy
Online Access:https://doi.org/10.1186/s12951-021-00963-9

Internet

https://doi.org/10.1186/s12951-021-00963-9

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