Bone and Soft-Tissue Sarcoma: A New Target for Telomerase-Specific Oncolytic Virotherapy

Adenovirus serotype 5 (Ad5) is widely and frequently used as a virus vector in cancer gene therapy and oncolytic virotherapy. Oncolytic virotherapy is a novel antitumor treatment for inducing lytic cell death in tumor cells without affecting normal cells. Based on the Ad5 genome, we have generated t...

Full description

Bibliographic Details
Main Authors: Hiroshi Tazawa, Joe Hasei, Shuya Yano, Shunsuke Kagawa, Toshifumi Ozaki, Toshiyoshi Fujiwara
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
gfp
p53
Online Access:https://www.mdpi.com/2072-6694/12/2/478