Exercise Prevents Enhanced Postoperative Neuroinflammation and Cognitive Decline and Rectifies the Gut Microbiome in a Rat Model of Metabolic Syndrome

Exercise Prevents Enhanced Postoperative Neuroinflammation and Cognitive Decline and Rectifies the Gut Microbiome in a Rat Model of Metabolic Syndrome

IntroductionPostoperative cognitive decline (PCD) can affect in excess of 10% of surgical patients and can be considerably higher with risk factors including advanced age, perioperative infection, and metabolic conditions such as obesity and insulin resistance. To define underlying pathophysiologic...

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Bibliographic Details
Main Authors: Xiaomei Feng, Yosuke Uchida, Lauren Koch, Steve Britton, Jun Hu, David Lutrin, Mervyn Maze
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
preoperative exercise
postoperative cognitive decline
postoperative neuroinflammation
microbiome
metabolic syndrome
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01768/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01768/full

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