Regulation of the Proteolytic Activity of Cysteine Cathepsins by Oxidants

Regulation of the Proteolytic Activity of Cysteine Cathepsins by Oxidants

Besides their primary involvement in the recycling and degradation of proteins in endo-lysosomal compartments and also in specialized biological functions, cysteine cathepsins are pivotal proteolytic contributors of various deleterious diseases. While the molecular mechanisms of regulation via their...

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Bibliographic Details
Main Authors: Gilles Lalmanach, Ahlame Saidi, Paul Bigot, Thibault Chazeirat, Fabien Lecaille, Mylène Wartenberg
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
cathepsin
chronic obstructive pulmonary disease (copd)
cysteine
cysteine protease
lung inflammation
oxidation
proteolysis
thiol
Online Access:https://www.mdpi.com/1422-0067/21/6/1944

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https://www.mdpi.com/1422-0067/21/6/1944

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