Astragalin Attenuates Dextran Sulfate Sodium (DSS)-Induced Acute Experimental Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting NF-κB Activation in Mice

Astragalin Attenuates Dextran Sulfate Sodium (DSS)-Induced Acute Experimental Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting NF-κB Activation in Mice

With the ulcerative colitis (UC) incidence increasing worldwide, it is of great importance to prevent and treat UC. However, efficient treatment options for UC are relatively limited. Due to the potentially serious adverse effects of existing drugs, there is an increasing demand for alternative cand...

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Bibliographic Details
Main Authors: Lei Peng, Xiaoyu Gao, Long Nie, Jing Xie, Tianyi Dai, Chongying Shi, Liang Tao, Yan Wang, Yang Tian, Jun Sheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
Astragalin
Escherichia-Shigella
gut microbiota
NF-κB
Ruminococcaceae
ulcerative colitis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02058/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02058/full

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