Cryo-thermal therapy inducing MI macrophage polarization created CXCL10 and IL-6-rich pro-inflammatory environment for CD4+ T cell-mediated anti-tumor immunity

Cryo-thermal therapy inducing MI macrophage polarization created CXCL10 and IL-6-rich pro-inflammatory environment for CD4+ T cell-mediated anti-tumor immunity

Purpose: We previously developed a novel cryo-thermal therapy to treat malignant mammary carcinoma and melanoma in a mouse model; long-term survival and CD4+ T cell orchestrating anti-tumor immune memory response were achieved. Moreover, cryo-thermal-induced CD4+ T cell differentiation into Th1 and...

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Bibliographic Details
Main Authors: Ping Liu, Shengguo Jia, Yue Lou, Kun He, Lisa X. Xu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:International Journal of Hyperthermia
Subjects:
cryo-thermal therapy
m1 macrophages polarization
cxcl10
il-6
cd4+ t cell differentiation
Online Access:http://dx.doi.org/10.1080/02656736.2019.1579373

Internet

http://dx.doi.org/10.1080/02656736.2019.1579373

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