Aberrant Apoptotic Response of Colorectal Cancer Cells to Novel Nucleoside Analogues.

Despite the increased understanding of colorectal cancer and the introduction of targeted drug therapy, the metastatic phase of the disease remains refractory to treatment. Since the deregulation of normal apoptosis contributes to the pathogenesis of colorectal cancer, novel nucleoside analogues wer...

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Bibliographic Details
Main Authors: Leonie Harmse, Nurit Dahan-Farkas, Jenny-Lee Panayides, Willem van Otterlo, Clement Penny
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0138607