A novel SYBR-based duplex qPCR for the detection of gene dosage: detection of an <it>APC</it> large deletion in a familial adenomatous polyposis patient with an unusual phenotype

A novel SYBR-based duplex qPCR for the detection of gene dosage: detection of an <it>APC</it> large deletion in a familial adenomatous polyposis patient with an unusual phenotype

<p>Abstract</p> <p>Background</p> <p>Familial adenomatous polyposis (FAP) is a hereditary colorectal cancer syndrome caused by a loss of function of the <it>APC</it> gene. Large deletions in <it>APC</it> are a common cause of FAP; despite the exi...

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Bibliographic Details
Main Authors: Torrezan Giovana, da Silva Felipe Cavalcanti, Krepischi Ana Cristina, dos Santos Érika Maria, Rossi Benedito, Carraro Dirce
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Medical Genetics
Subjects:
Gene dosage
Quantitative PCR
Familial adenomatous polyposis
<it>APC</it> whole gene deletion
Online Access:http://www.biomedcentral.com/1471-2350/13/55

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http://www.biomedcentral.com/1471-2350/13/55

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