Protein-protein interactions in clathrin vesicular assembly: radial distribution of evolutionary constraints in interfaces.

In eukaryotic organisms clathrin-coated vesicles are instrumental in the processes of endocytosis as well as intracellular protein trafficking. Hence, it is important to understand how these vesicles have evolved across eukaryotes, to carry cargo molecules of varied shapes and sizes. The intricate n...

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Bibliographic Details
Main Authors: Rupali A Gadkari, Narayanaswamy Srinivasan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3285160?pdf=render