Human umbilical cord-derived mesenchymal stem cells do not undergo malignant transformation during long-term culturing in serum-free medium.

BACKGROUND:Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are in the foreground as a preferable application for treating diseases. However, the safety of hUC-MSCs after long-term culturing in vitro in serum-free medium remains unclear. METHODS:hUC-MSCs were separated by adherent tiss...

Full description

Bibliographic Details
Main Authors: Gecai Chen, Aihuan Yue, Zhongbao Ruan, Yigang Yin, RuZhu Wang, Yin Ren, Li Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4041760?pdf=render