Human umbilical cord-derived mesenchymal stem cells do not undergo malignant transformation during long-term culturing in serum-free medium.
BACKGROUND:Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are in the foreground as a preferable application for treating diseases. However, the safety of hUC-MSCs after long-term culturing in vitro in serum-free medium remains unclear. METHODS:hUC-MSCs were separated by adherent tiss...
Main Authors: | Gecai Chen, Aihuan Yue, Zhongbao Ruan, Yigang Yin, RuZhu Wang, Yin Ren, Li Zhu |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4041760?pdf=render |
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