In utero exposure to diesel exhaust is associated with alterations in neonatal cardiomyocyte transcription, DNA methylation and metabolic perturbation

In utero exposure to diesel exhaust is associated with alterations in neonatal cardiomyocyte transcription, DNA methylation and metabolic perturbation

Abstract Background Developmental exposure to particulate matter air pollution is harmful to cardiovascular health, but the mechanisms by which this exposure mediates susceptibility to heart disease is poorly understood. We have previously shown, in a mouse model, that gestational exposure to diesel...

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Bibliographic Details
Main Authors: Jamie M. Goodson, James W. MacDonald, Theo K. Bammler, Wei-Ming Chien, Michael T. Chin
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Particle and Fibre Toxicology
Subjects:
Diesel
PM2.5
Transcription
DNA methylation
Metabolism
Online Access:http://link.springer.com/article/10.1186/s12989-019-0301-9

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http://link.springer.com/article/10.1186/s12989-019-0301-9

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