Severe pandemic H1N1 2009 infection is associated with transient NK and T deficiency and aberrant CD8 responses.

Severe pandemic H1N1 2009 infection is associated with transient NK and T deficiency and aberrant CD8 responses.

It is unclear why the severity of influenza varies in healthy adults or why the burden of severe influenza shifts to young adults when pandemic strains emerge. One possibility is that cross-protective T cell responses wane in this age group in the absence of recent infection. We therefore compared t...

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Bibliographic Details
Main Authors: Annette Fox, Nguyen Minh Hoa Le, Peter Horby, H Rogier van Doorn, Vu Trung Nguyen, Hong Ha Nguyen, Trung Cap Nguyen, Dinh Phu Vu, Minh Ha Nguyen, Nguyen Thi Ngoc Diep, Vu Thi Ngoc Bich, Huong Tran Thi Kieu Huong, Walter R Taylor, Jeremy Farrar, Heiman Wertheim, Van Kinh Nguyen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3282732?pdf=render

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http://europepmc.org/articles/PMC3282732?pdf=render

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