Potential Impact of COMT-rs4680 G > A Gene Polymorphism in Coronary Artery Disease

Potential Impact of COMT-rs4680 G > A Gene Polymorphism in Coronary Artery Disease

Purpose: Catechol-O-methyltransferase (COMT) plays a central role in DNA repair and estrogen-induced carcinogenesis. The nonsynonymous single nucleotide polymorphism (SNP) in exon 4 G > A or Val108 > 158Met or rs4680 G > A influences COMT enzyme activity. The three phenotypes of...

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Bibliographic Details
Main Authors: Rashid Mir, Musadiq Bhat, Jamsheed Javid, Chandan Jha, Alpana Saxena, Shaheen Banu
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
catechol-O-methyltransferase (COMT)
coronary artery disease (CAD)
allele specific PCR-AS-PCR
COMT Val158Met
COMT G &gt
A
Online Access:http://www.mdpi.com/2308-3425/5/3/38

Internet

http://www.mdpi.com/2308-3425/5/3/38

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