Identification of differentially expressed proteins from Leishmania amazonensis associated with the loss of virulence of the parasites.

BACKGROUND: The present study analyzed whether or not the in vitro cultivation for long periods of time of pre-isolated Leishmania amazonensis from lesions of chronically infected BALB/c mice was able to interfere in the parasites' infectivity using in vivo and in vitro experiments. In addition...

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Main Authors: Rubens D M Magalhães, Mariana C Duarte, Eliciane C Mattos, Vivian T Martins, Paula S Lage, Miguel A Chávez-Fumagalli, Daniela P Lage, Daniel Menezes-Souza, Wiliam C B Régis, Maria J Manso Alves, Manuel Soto, Carlos A P Tavares, Ronaldo A P Nagen, Eduardo A F Coelho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3974679?pdf=render