Natural Killer (NK) Cell Education Differentially Influences HIV Antibody-Dependent NK Cell Activation and Antibody-Dependent Cellular Cytotoxicity

Immunotherapy using broadly neutralizing antibodies (bNAbs) endowed with Fc-mediated effector functions has been shown to be critical for protecting or controlling viral replication in animal models. In human, the RV144 Thai trial was the first trial to demonstrate a significant protection against H...

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Bibliographic Details
Main Authors: Nicole F. Bernard, Zahra Kiani, Alexandra Tremblay-McLean, Sanket A. Kant, Christopher E. Leeks, Franck P. Dupuy
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01033/full