Single nucleotide polymorphisms of cytokine-related genes and association with clinical outcome in a Chagas disease case-control study from Brazil

Single nucleotide polymorphisms of cytokine-related genes and association with clinical outcome in a Chagas disease case-control study from Brazil

BACKGROUND The severity of chronic chagasic cardiomyopathy (CCC), the most frequent clinical outcome of Chagas disease (CD), has been associated with cytokine-enriched heart tissue inflammation, and high serum levels of transforming growth factor (TGFβ), interferon-gamma (IFNγ), and tumour necrosis...

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Bibliographic Details
Main Authors: Lucia Elena Alvarado-Arnez, Angelica Martins Batista, Silvia Marinho Alves, Gloria Melo, Virgínia Maria Barros de Lorena, Cynthia C Cardoso, Isabela Resende Pereira, Cristina Carrazzone, Antonio G Pacheco, Wilson Oliveira Jr, Milton Ozório Moraes, Joseli Lannes-Vieira
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2018-05-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Chagas disease
Trypanosoma cruzi
cardiomyopathy
cytokines
gene polymorphism
meta-analysis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018000600301&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018000600301&lng=en&tlng=en

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