In vivo knockdown of Piccolino disrupts presynaptic ribbon morphology in mouse photoreceptor synapses

In vivo knockdown of Piccolino disrupts presynaptic ribbon morphology in mouse photoreceptor synapses

Piccolo is the largest known cytomatrix protein at active zones of chemical synapses. A growing number of studies on conventional chemical synapses assign Piccolo a role in the recruitment and integration of molecules relevant for both endo- and exocytosis of synaptic vesicles, the dynamic assembly...

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Bibliographic Details
Main Authors: Hanna eRegus-Leidig, Michaela eFuchs, Martina eLöhner, Sarah eLeist, Sergio eLeal-Ortiz, Vince eChiodo, William eHauswirth, Craig eGarner, Johann Helmut Brandstätter
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Retina
active Zone
ribbon synapse
RIBEYE
Piccolino
Piccolo
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00259/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00259/full

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