LRRK2 levels in immune cells are increased in Parkinson’s disease

Immune system regulation: A known suspect High levels of leucine-rich repeat kinase 2 (LRRK2) in immune cells disrupt immune system function in patients with Parkinson’s disease (PD). Mutations in LRRK2 are the most common genetic cause of PD. Although LRRK2 is found in many immune cells, research e...

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Bibliographic Details
Main Authors: D. A. Cook, G. T. Kannarkat, A. F. Cintron, Laura M. Butkovich, Kyle B. Fraser, J. Chang, N. Grigoryan, S. A. Factor, Andrew B. West, J. M. Boss, M. G. Tansey
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-017-0010-8