alpha-Actinin interacts with rapsyn in agrin-stimulated AChR clustering

<p/> <p>AChR is concentrated at the postjunctional membrane at the neuromuscular junction. However, the underlying mechanism is unclear. We show that α-actinin, a protein known to cross-link F-actin, interacts with rapsyn, a scaffold protein essential for neuromuscular junction formation...

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Bibliographic Details
Main Authors: Dobbins G Clement, Luo Shiwen, Yang Zhihua, Xiong Wen C, Mei Lin
Format: Article
Language:English
Published: BMC 2008-12-01
Series:Molecular Brain
Online Access:http://www.molecularbrain.com/content/1/1/18