p16 as an independent marker for detection of high-risk HPV in oral submucous fibrosis and oral squamous cell carcinoma

p16 as an independent marker for detection of high-risk HPV in oral submucous fibrosis and oral squamous cell carcinoma

Background: An alarming increase in incidence of high-risk human papillomavirus (HPV) positive tumors in head and neck squamous cell carcinoma (HNSCC) by 25% and 70% in oropharyngeal HNSCC cannot be ignored. The early oncogenes of HPV, E6, and E7 play a key role in carcinogenesis. HPV associated tum...

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Bibliographic Details
Main Authors: Archana Sudhakaran, Kaveri Hallikeri, Biji Babu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
High risk
human papillomavirus
immunohistochemistry
oral squamous cell carcinoma
oral submucous fibrosis
p16
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2019;volume=62;issue=4;spage=523;epage=528;aulast=Sudhakaran

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http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2019;volume=62;issue=4;spage=523;epage=528;aulast=Sudhakaran

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