Degradable Spirocyclic Polyacetal-Based Core-Amphiphilic Assemblies for Encapsulation and Release of Hydrophobic Cargo

Degradable Spirocyclic Polyacetal-Based Core-Amphiphilic Assemblies for Encapsulation and Release of Hydrophobic Cargo

Polymeric nanomaterials that degrade in acidic environments have gained considerable attention in nanomedicine for intracellular drug delivery and cancer therapy. Among various acid-degradable linkages, spirocyclic acetals have rarely been used to fabricate such vehicles. In addition to acid sensiti...

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Bibliographic Details
Main Authors: Brandon Andrade-Gagnon, Marilyne Bélanger-Bouliga, Phuong Trang Nguyen, Thi Hong Diep Nguyen, Steve Bourgault, Ali Nazemi
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Nanomaterials
Subjects:
pH-degradable nanoparticles
spirocyclic polyacetals
drug delivery
cytocompatibility
stimuli-responsive nanomaterials
Online Access:https://www.mdpi.com/2079-4991/11/1/161

Internet

https://www.mdpi.com/2079-4991/11/1/161

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