Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis
<p>Abstract</p> <p>Background</p> <p>Single genome-wide screens for the effect of altered gene dosage on drug sensitivity in the model organism <it>Saccharomyces cerevisiae </it>provide only a partial picture of the mechanism of action of a drug.</p> &...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-01-01
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Series: | BMC Microbiology |
Online Access: | http://www.biomedcentral.com/1471-2180/9/9 |