Platelets, immune cells and the coagulation cascade; friend or foe of the circulating tumour cell?

Abstract Cancer cells that transit from primary tumours into the circulatory system are known as circulating tumour cells (CTCs). These cancer cells have unique phenotypic and genotypic characteristics which allow them to survive within the circulation, subsequently extravasate and metastasise. CTCs...

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Bibliographic Details
Main Authors: Mark P. Ward, Laura E. Kane, Lucy A. Norris, Bashir M. Mohamed, Tanya Kelly, Mark Bates, Andres Clarke, Nathan Brady, Cara M. Martin, Robert D. Brooks, Doug A. Brooks, Stavros Selemidis, Sean Hanniffy, Eric P. Dixon, Sharon A. O’Toole, John J. O’Leary
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Molecular Cancer
Online Access:https://doi.org/10.1186/s12943-021-01347-1