Meis1: effects on motor phenotypes and the sensorimotor system in mice

Meis1: effects on motor phenotypes and the sensorimotor system in mice

MEIS1 encodes a developmental transcription factor and has been linked to restless legs syndrome (RLS) in genome-wide association studies. RLS is a movement disorder leading to severe sleep reduction and has a substantial impact on the quality of life of patients. In genome-wide association studies,...

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Bibliographic Details
Main Authors: Aaro V. Salminen, Lillian Garrett, Barbara Schormair, Jan Rozman, Florian Giesert, Kristina M. Niedermeier, Lore Becker, Birgit Rathkolb, Ildikó Rácz, German Mouse Clinic Consortium, Martin Klingenspor, Thomas Klopstock, Eckhard Wolf, Andreas Zimmer, Valérie Gailus-Durner, Miguel Torres, Helmut Fuchs, Martin Hrabě de Angelis, Wolfgang Wurst, Sabine M. Hölter, Juliane Winkelmann
Format: Article
Language:English
Published: The Company of Biologists 2017-08-01
Series:Disease Models & Mechanisms
Subjects:
Meis1
Prepulse inhibition
Restless legs syndrome
Sensorimotor system
Mouse model
Pramipexole
Online Access:http://dmm.biologists.org/content/10/8/981

Internet

http://dmm.biologists.org/content/10/8/981

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