The Prognostic Role of SIRT1-Autophagy Axis in Gastric Cancer

Aim. Sirtuin 1 (SIRT1) can induce autophagy through deacetylation of Beclin-1 and other autophagy mediators. However, the relationship between SIRT1 and autophagy in GC has not been defined. Therefore, the aim of this study was to confirm the prognostic value of SIRT1 and Beclin-1 and their relation...

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Bibliographic Details
Main Authors: Guanglin Qiu, Xuqi Li, Chao Wei, Xiangming Che, Shicai He, Jing Lu, Shufeng Wang, Ke Pang, Lin Fan
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2016/6869415