Treatment with the antipsychotic agent, risperidone, reduces disease severity in experimental autoimmune encephalomyelitis.

Treatment with the antipsychotic agent, risperidone, reduces disease severity in experimental autoimmune encephalomyelitis.

Recent studies have demonstrated that atypical antipsychotic agents, which are known to antagonize dopamine D2 and serotonin 5-HT2a receptors, have immunomodulatory properties. Given the potential of these drugs to modulate the immune system both peripherally and within the central nervous system, w...

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Bibliographic Details
Main Authors: David O'Sullivan, Laura Green, Sarrabeth Stone, Pirooz Zareie, Marie Kharkrang, Dahna Fong, Bronwen Connor, Anne Camille La Flamme
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4130540?pdf=render

Internet

http://europepmc.org/articles/PMC4130540?pdf=render

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