Novel signal peptides improve the secretion of recombinant Staphylococcus aureus Alpha toxinH35L in Escherichia coli

Novel signal peptides improve the secretion of recombinant Staphylococcus aureus Alpha toxinH35L in Escherichia coli

Abstract Secretion of heterologous proteins into Escherichia coli cell culture medium offers significant advantages for downstream processing over production as inclusion bodies; including cost and time savings, and reduction of endotoxin. Signal peptides play an important role in targeting proteins...

Full description

Bibliographic Details
Main Authors: SooJin Han, Shushil Machhi, Mark Berge, Guoling Xi, Thomas Linke, Ronald Schoner
Format: Article
Language:English
Published: SpringerOpen 2017-05-01
Series:AMB Express
Subjects:
Alpha toxin
Escherichia coli
Extracellular secretion
Periplasmic translocation
Signal peptides
Signal peptide recognition particle
Online Access:http://link.springer.com/article/10.1186/s13568-017-0394-1

Internet

http://link.springer.com/article/10.1186/s13568-017-0394-1

Similar Items