ERG-28 controls BK channel trafficking in the ER to regulate synaptic function and alcohol response in C. elegans

ERG-28 controls BK channel trafficking in the ER to regulate synaptic function and alcohol response in C. elegans

Voltage- and calcium-dependent BK channels regulate calcium-dependent cellular events such as neurotransmitter release by limiting calcium influx. Their plasma membrane abundance is an important factor in determining BK current and thus regulation of calcium-dependent events. In C. elegans, we show...

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Bibliographic Details
Main Authors: Kelly H Oh, James J Haney, Xiaohong Wang, Chiou-Fen Chuang, Janet E Richmond, Hongkyun Kim
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-02-01
Series:eLife
Subjects:
alcohol
BK channel
synaptic transmission
Online Access:https://elifesciences.org/articles/24733

Internet

https://elifesciences.org/articles/24733

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