The Effect of Arginine as an Anti-Aggregation Excipient on Recombinant Human Growth Hormone

Aggregation is one of the main physical instabilities of proteins, which might occur during all steps of the manufacturing and storage of products. The presence of protein aggregates may result in the reduction of activity, induce immunologic responses and failure of therapeutic efficiency. Therefor...

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Bibliographic Details
Main Authors: Mehrdad Pazhouhandeh, Faranak Salmannejad, Nastaran Nafissi-Varcheh, Maryam Tabarzad
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2016-10-01
Series:Trends in Peptide and Protein Sciences
Subjects:
Online Access:https://journals.sbmu.ac.ir/protein/article/view/13040