Fibroblast growth factor 23 is upregulated in the kidney in a chronic kidney disease rat model.

The hormone fibroblast growth factor 23 (FGF23) is secreted from bone and is involved in phosphorus (P) metabolism. FGF23 mainly binds the FGF receptor, which interacts with αKlotho in the kidney or parathyroid and regulates Na-dependent phosphate co-transporter type IIa (NaPi-IIa) and type IIc (NaP...

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Bibliographic Details
Main Authors: Hidekazu Sugiura, Ai Matsushita, Mayuko Futaya, Atsuko Teraoka, Ken-Ichi Akiyama, Noriyoshi Usui, Nobuo Nagano, Kosaku Nitta, Ken Tsuchiya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5843171?pdf=render